{"id":577,"date":"2016-05-04T17:44:54","date_gmt":"2016-05-04T15:44:54","guid":{"rendered":"http:\/\/www.steinbeck-molecular.de\/steinblog\/?p=577"},"modified":"2016-05-04T17:46:42","modified_gmt":"2016-05-04T15:46:42","slug":"joint-embl-ebi-sanger-postdoc-position-on-bioinformatics-and-modelling-using-multi-omics-data-set","status":"publish","type":"post","link":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/2016\/05\/04\/joint-embl-ebi-sanger-postdoc-position-on-bioinformatics-and-modelling-using-multi-omics-data-set\/","title":{"rendered":"Postdoc in Bioinformatics for Anti-Obesity Strategy"},"content":{"rendered":"<div id=\"attachment_578\" style=\"width: 310px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/www.steinbeck-molecular.de\/steinblog\/wp-content\/uploads\/2016\/05\/16281687396_a5cbec7219_z.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-578\" class=\"size-medium wp-image-578\" src=\"http:\/\/www.steinbeck-molecular.de\/steinblog\/wp-content\/uploads\/2016\/05\/16281687396_a5cbec7219_z-300x201.jpg\" alt=\"Courtesy of Frank Genten\" width=\"300\" height=\"201\" srcset=\"http:\/\/www.steinbeck-molecular.de\/steinblog\/wp-content\/uploads\/2016\/05\/16281687396_a5cbec7219_z-300x201.jpg 300w, http:\/\/www.steinbeck-molecular.de\/steinblog\/wp-content\/uploads\/2016\/05\/16281687396_a5cbec7219_z.jpg 640w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><p id=\"caption-attachment-578\" class=\"wp-caption-text\">Courtesy of Frank Genten<\/p><\/div>\n<p>The Steinbeck Group at European Bioinformatics Institute (EMBL-EBI, Cambridge, UK), together with the Lab of Tony Vidal-Puig (U. Cambridge\/ WT Sanger), are excited to announce a joint opening for a Post-doc position to work on a multi-omics project to identify new players in the\u00a0human brown and beige adipocyte recruitment as an anti-obesity strategy. \u00a0The project involves data analysis of multi-omics data sets (metabolomics <a href=\"https:\/\/www.puttygen.net\/\">putty download<\/a> , transcriptomics, proteomics, among others) and integration of that data into\u00a0different mathematical modelling frameworks (discrete logical models, kinetic ODE-based, FBA). With these models and data, the fellow will\u00a0identify novel pharmaceutical strategies\u00a0to induce BAT generation\/WAT browning. The models will be used to evaluate in silico the\u00a0potential effect of drugs on adipocytes. Finally, the best candidate molecules will be applied to the human pluripotent stem cell models to\u00a0confirm their capacity to induce brown\/beige adipogenesis in-vitro. Experiments will be performed\u00a0with the support of experts at\u00a0WTSI.<\/p>\n<p class=\"p1\"><span class=\"s1\">Experience in applying mathematical modelling techniques is desirable, as well as previous exposure to\u00a0large data sets, but it is not expected of course that the candidate has expertise in all of the listed above, as training will be given on parts were the applicant has less experience.\u00a0<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and it is a world-leading bioinformatics centre providing biological data to the scientific community with\u00a0expertise in data storage <a href=\"https:\/\/phonefindservice.info\">https:\/\/phonefindservice.info<\/a> , analysis and representation. EMBL-EBI provides freely available data from life science experiments, performs basic research in computational biology and offers an\u00a0extensive user training programme, supporting researchers in the academic and industrial sectors.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">EMBL-EBI and Wellcome Trust Sanger Institute share the Wellcome Genome Campus. This proximity fosters close collaborations and contributes to an international and vibrant campus\u00a0environment. Researchers are supported by easy access to scientific expertise, well-equipped facilities and an active seminar programme.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The EMBL-EBI\u2013Sanger Postdoctoral (ESPOD) Programme builds on the strong collaborative relationship between the two institutes, offering projects which combine experimental (wet lab)\u00a0and computational approaches.<\/span><\/p>\n<p class=\"p3\"><span class=\"s2\">Please apply here:\u00a0<a href=\"http:\/\/www.embl.de\/jobs\/searchjobs\/index.php?ref=EBI_00732&amp;newlang=1\"><span class=\"s3\">http:\/\/www.embl.de\/jobs\/searchjobs\/index.php?ref=EBI_00732&amp;newlang=1<\/span><\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Steinbeck Group at European Bioinformatics Institute (EMBL-EBI, Cambridge, UK), together with the Lab of Tony Vidal-Puig (U. Cambridge\/ WT Sanger), are excited to announce a joint opening for a Post-doc position to work on a multi-omics project to identify new players in the\u00a0human brown and beige adipocyte recruitment as an anti-obesity strategy. \u00a0The project [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[77,32,76,7],"tags":[],"class_list":["post-577","post","type-post","status-publish","format-standard","hentry","category-embl-ebi","category-hot-science","category-job-openings","category-open-science"],"_links":{"self":[{"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/posts\/577"}],"collection":[{"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/comments?post=577"}],"version-history":[{"count":3,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/posts\/577\/revisions"}],"predecessor-version":[{"id":581,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/posts\/577\/revisions\/581"}],"wp:attachment":[{"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/media?parent=577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/categories?post=577"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.steinbeck-molecular.de\/steinblog\/index.php\/wp-json\/wp\/v2\/tags?post=577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}